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Artificial Intelligence in multitargeting approaches in chronic recalcitrant diseases
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Therapy areas: Respiratory, Dermatology, Inflammation, Cardio-Metabolic, Chronic Pain and Oncology
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Indications: Broad (Block buster approach), targeted (personalized treatment approach), orphan, niche
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Disease Biology: Extensive background of novel targets, chronic disease mechanisms, cellular / biochemical / immune / genomic / proteomic disease signatures, disease heterogeneity and endotypes, biomarkers for patient stratification, treatment algorithms, unmet medical needs, global pipeline molecules and competitive positioning
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New Drug Discovery Research
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Therapeutic targets: First in class vs Best in class, Kinases, GPCRs, Enzymes / Ion Channels / Transcription Factors and others
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Route of administration: Oral, inhaled, topical on skin
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Preclinical research strategy: road map / milestones / GO-NO GO decision gates
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Preclinical development: Target to IND lead nomination
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Preclinical, translational and early human POC study designs
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NCE out-licensing: Preclinical data package, confidential presentations, due diligence meetings
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Extensive experience in research collaborations with world-class Research Institutes, Universities and CROs. A broad network of international scientific experts for external advice
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Establishment of Discovery Biology Lab
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Branded specialty drug products:
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McAb-drug conjugates
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Scientific evaluation and guidance on global in-licensing opportunities to Global Business Development and Portfolio team
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Ideation of novel, differentiated molecule for quick market entry - single agent or fixed dose combination
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Health & Wellness:
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Microbiome based and other Consumer Products, Nutraceuticals
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